Acetyl Hexapeptide-3 (Argireline) inhibits the release of neurotransmitters as it interferes with the formation and stabilization of the protein complex needed for docking vesicles of acetylcholine release. Acetyl Hexapeptide-3 (Argireline) inhibits the release of neurotransmitters as it interferes with the formation and stabilization of the protein complex needed for docking vesicles of acetylcholine release. In an open study often female subjects, a serum containing this peptide was applied twice a day. After 1 month, the results showed a reduction in periorbital wrinkle depth of 27%. The in vitro effect of neurotransmitter-inhibiting peptides is to inhibit the release of neurotransmitters, while the desired, in vivo, effect is to reduce facial wrinkles caused by a decrease in muscle activity. Research tests were performed using a combination of both actives in order to evaluate a possible synergy or additive effect. A cream/serum containing 5% argireline solution (0.05%) and 5% leuphasyl solution (0.05%) was applied twice daily around the eyes of 15 volunteers, aged 39 to 63, for 28 days. A decrease of 24.62% was accomplished, with maximum values up to –46.53%. Both peptides show additive effects due to their complementary mechanisms.
Sequence:Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 or Ac-EEMQRR-NH2
Molecular formula: C34H60N14O12S
Molecular weight: : 888.99
Argireline is the trade name for Acetyl Hexapeptide-3, a synthetic anti-aging cosmetic peptide derived from natural proteins. It is a peptide chain made up of amino acids. Argireline has been shown in research studies to help decrease the visible effects of aging by helping to reduce the deep wrinkles and lines that occur around the forehead and eyes. Resultanty, a large number of cosmetics companies include Argireline in the formulation of their anti-aging products. These products include creams, lotions, serums, body milks, eye creams, gels and emulsions.
Chemically, when applied as a solution to specific areas of the face, Argireline inhibits the reactions that cause muscles to move or contract - for example when forming facial expressions such as smiling or frowning. In theory, repetitive muscle movements create lines and wrinkles and it is believed the attenuation of muscular contractions can reduce the depth of existing wrinkles and prevent the formation of new lines. Research studies have found that Argireline has been shown to produce a significant anti-aging effect. within the skin.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping 3-4 months reconstituted (mixed with bacteriostatic water) to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you're ready to reconstitute it with bacteriostatic water.
Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.
However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.
Read Reviews from our satisfied customers. Share your experience with Us by clicking the below button!
Biogen Peptides has been my go-to source for research-grade peptides. The quality and consistency are unmatched, and the customer service is always top-notch.
Excellent purity and fast shipping! Biogen Peptides is truly dedicated to supporting research professionals with top-quality products.
Biogen Peptides consistently delivers top-quality products. The purity of their peptides has enhanced the reliability of my research outcomes.