Oxytocin 10mg (6000 IU)

Oxytocin Overview

Oxytocin is best thought of as one protein with two separate natural functions. First, it is a neuropeptide released by the hypothalamus to play important roles in bonding, sexual reproduction, and childbirth. Oxytocin is also a standard blood borne hormone, however, one that is produced by the placenta of pregnant women and that has effects on childbirth, milk production, and bonding with newborns. In men, a small amount of oxytocin is produced in the testes to play a role in mating behavior and pair bonding. Research on oxytocin has revealed it to play roles.

What Is Oxytocin?

Oxytocin is a short peptide, just nine amino acids in length, produced in the hypothalamus and released by the posterior pituitary. It is also produced by the placenta, ovaries, and testes. Like many peptide hormones, oxytocin starts out life as a much larger precursor molecule that is subsequently cleaved to create the active hormone. Interestingly, oxytocin has also been found to be produced in the retina, the adrenal glands, and thymus, and the pancreas. Though oxytocin is generally regarded as a neurohypophysial hormone, this thinking is increasingly being thought of as outdated as the potential effects of the peptide increase to include a number of different tissues.

Oxytocin Research

Oxytocin in Wound Healing

Oxytocin can actually modulate inflammation via action on certain inflammatory cytokines. An interesting experiment looking at rates of wound healing in 37 couples found that social interaction that led to higher oxytocin levels actually increased the rate of wound healing. The higher the oxytocin level, the greater the rate of wound healing

Studying Oxytocin in Cardiovascular Risk

Based on its ability to improve rates of wound healing and modulate inflammatory cytokines, researchers speculated that oxytocin may also play a role in protecting the heart and vascular system. The peptide has been found to help lower fat mass, improve glucose tolerance, decrease blood pressure, and relieve anxiety

There is also good evidence to suggest that atherosclerosis develops, in certain settings, as a result of suppressing expression of the oxytocin receptor. Increasing oxytocin levels in people with reduced receptor density can maintain cardiovascular integrity and, in some cases, can reverse atherosclerosis

Research in rats suggests that oxytocin infusion directly into the heart during ischemia (e.g. heart attack) can protect cardiomyocytes (heart muscle cells) from death. According to Jankoski et. al., chronic oxytocin treatment can prevent the late-term development of dilated cardiomyopathy and may be useful to precondition cardiac stem cells to aid in “tissue regeneration through direct differentiation, secretion of protective and cardiomyogenic factors, and/or their fusion with injured cardiomyocytes

Oxytocin actually appears to protect against ischemic injuries in a number of tissues and may not be strictly active in heart tissue. Research in rats with priapism (persistent erection) indicates that oxytocin administration protects against ischemia-reperfusion injury by reducing nitric oxide levels

Diabetes Management

Oxytocin likely increases glucose uptake by skeletal by boosting insulin sensitivity, making it of potential use in treating diabetes. Research in mice has also revealed that oxytocin plays important roles in lipid utilization, reducing total body fat mass and rates of dyslipidemia. Deficiencies in oxytocin have been shown to cause obesity even in the setting of normal food intake and exercise activity, suggesting that the peptide plays critical roles in energy homeostasis

Research in lean and obese mice, interestingly, has shown that oxytocin treatment has no effect on glucose, insulin, and body composition in lean mice. It appears only to affect these parameters in obese mice, suggesting that while the peptide is useful in treating certain aspects of diabetes, it may not be suitable in all settings

Oxytocin Research and Hunger

Research in a condition (Prader-Willi syndrome) marked by uncontrolled appetite has revealed that at least part of the pathology results from increased suppression, above normal, of oxytocin signaling. There is now reason to believe that oxytocin plays a role in the regulation of hunger state and may even play a direct role in feeding behavior

Oxytocin and Old Muscle

A new finding suggests that oxytocin is a critical component of healthy muscle maintenance and repair and that declines in oxytocin signaling with aging are at least partly responsible for age-related muscle wasting (sarcopenia). The research, carried out at Berkeley, suggests that as blood levels of oxytocin decline with age, so do the numbers of oxytocin receptors on muscle stem cells. Administering oxytocin, however, reverse this effect in just days, allowing muscles to recover much of their potential for healing. This is important because breakdown and repair is the natural process by which muscle is maintained and built. According to Elabd, one of the authors of the research, “repair of muscle in the old mice was at about 80 percent” of what was seen in younger mice after oxytocin was administered. There is hope that oxytocin might offer a meaningful way to intervene in age-related organ degeneration and thus slow dysfunction

Oxytocin exhibits minimal side effects, low oral and excellent subcutaneous bioavailability in mice. Per kg dosage in mice does not scale to humans. Oxytocin for sale at Peptide Sciences is limited to educational and scientific research only, not for human consumption. Only buy Oxytocin if you are a licensed researcher.

Storage Instructions:

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping 3-4 months reconstituted (mixed with bacteriostatic water) to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you're ready to reconstitute it with bacteriostatic water.

Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.

However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.