SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles
The synthesis of SNAP-8 involves a final freeze-drying step. Freeze-dried products are commonly obtained as a polymorphous crystalline powder, which means that locally some aggregates and differences in crystal size may appear. This polymorphism is not associated to chemical differences and extensive work performed by the analytical department has ensured the homogeneity of the product. SNAP-8 is presented either as, an aqueous solution containing 0.5 g/L of the powder version. It can be incorporated at the final stage of the manufacturing product, provided the temperature is below 40 degrees Celsius. Taking into consideration the concentration of peptide in, it is recommended that 3 to 10% of the solution is present in the final formulation in order to obtain significant anti-wrinkle activity.
SNAP-8 Solution must be kept in a cool, dark and clean place to ensure a shelf life of at least twelve months. For long term storage it is recommended to store both forms at 4 ºC which extends shelf life to at least eighteen months. In rare cases, refrigerated storage.
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping 3-4 months reconstituted (mixed with bacteriostatic water) to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you're ready to reconstitute it with bacteriostatic water.
Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.
However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.
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